2015年3月26日星期四

Imidazenil|buy from supplier D&C Chemicals

Imidazenil|buy from supplier D&C Chemicals
DC Chemicals supplies: Imidazenil,cas: 151271-08-8,Catalog: DC7693,In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643258;

Product name: Imidazenil, Synonyms: UNII-7N95V6864R, cas: 151271-08-8, MW: 399.216483, Molecule Formula: C18H12BrFN4O 

Imidazenil, purity: >98%, Best price from D&C Chemicals. Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.

Imidazenil is a GABAA partial agonist with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold, and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.

This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance or dependence, reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.

Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety, a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents, and as a novel treatment for schizophrenia.For the detailed information about the solubility of Imidazenil  in water, the solubility of Imidazenil  in DMSO, the solubility of Imidazenil  in PBS buffer, the animal experiment of Imidazenil ,the in vivo and in vitro test of Imidazenil ,the cell experiment of Imidazenil ,the IC50 and EC50 of Imidazenil  please contact DC Chemicals.

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