2015年3月31日星期二

calpeptin supplier||DC Chemicals

calpeptin supplier||DC Chemicals
DC Chemicals provides calpeptin, other names: , cas: 117591-20-5. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643297;

calpeptin  is Ca2+-dependent protease,calpain inhibitor


calpeptin, other names: , cas: 117591-20-5, Molecule formular: , Molecule Weight: , Chemical name: benzyl N-[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]carbamate

Calpeptin is a cell permeable calpain inhibitor. Research shows that Calpeptin is an effective inhibitor of calpain 2 and can fully block cleavage of PLC-β 3 enzymes. Additionally, Calpeptin has demonstrated the ability to inhibit the activities of cathepsin L and calpain-1. In muscle cell studies Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. Pulmonary fibrosis research in mice have reported that Calpeptin can decrease expression of TGF-β1, IL-6, collage type Iα1, and angiopoietin-1 mRNA. Calpeptin is an inhibitor of Calpain 1, cathepsin K, cathepsin L and PTP. Calpeptin is an activator of Rock. For the detailed information of calpeptin, the solubility of calpeptin in water, the solubility of calpeptin in DMSO, the solubility of calpeptin in PBS buffer, the animal experiment (test) of  calpeptin, the cell expriment (test) of calpeptin, the in vivo, in vitro and clinical trial test of calpeptin, the EC50, IC50,and affinity,of calpeptin, Please contact DC Chemicals.

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