2015年3月31日星期二

LY2584702 supplier|LY-2584702|DC Chemicals

LY2584702 supplier|LY-2584702|DC Chemicals
DC Chemicals provides LY2584702, other names: LY-2584702,LY 2584702, cas: 1082949-67-4. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643273;

LY-2584702 is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.

LY2584702, other names: LY-2584702,LY 2584702, cas: 1082949-67-4, Molecule formular: C21H19F4N7, Molecule Weight: 445.42, Chemical name: 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-imidazol-2-yl]-1-piperidyl]-1H-pyrazolo[3,4-d]pyrimidine

LY-2584702 is an orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. LY2584702 inhibits ribosomal protein S6 Kinase (p70S6K), and prevents phosphorylation of the S6 subunit of ribosomes, thereby inhibiting normal ribosomal function within tumor cells leading to a decrease in protein synthesis and in cellular proliferation. P70S6K, a serine/threonine kinase, acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway, is often upregulated in a variety of cancer cells, and is involved in the regulation of cell growth, proliferation, motility, and survival. For the detailed information of LY2584702, the solubility of LY2584702 in water, the solubility of LY2584702 in DMSO, the solubility of LY2584702 in PBS buffer, the animal experiment (test) of  LY2584702, the cell expriment (test) of LY2584702, the in vivo, in vitro and clinical trial test of LY2584702, the EC50, IC50,and affinity,of LY2584702, Please contact DC Chemicals.

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