DC Chemicals supplies: STF-118804,cas: 894187-61-2,Catalog: DC7573,In stock.
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Product name: STF-118804, Synonyms: AGN-PC-0329XY, AKOS001906141, MCULE-5035356713, STF-118804, cas: 894187-61-2, MW: 461.53, Molecule Formula: C25H23N3O4S
STF-118804, cas 894187-61-2, Purity>98%. Best price and quality from DC Chemicals. AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1
STF-118804 reduces the viability of B-ALL cell lines containing MLL chromosomal translations, with IC50 values in the low nanomolar range. In addition, leukemic samples from ?ve pediatric ALL patients are also sensitive to STF-118804 in the low nanomolar range. STF-118804 induces leukemia MV411 cell apoptosis without antecedent cell cycle arrest. [1] STF-118804 (25 mg/kg twice daily, s.c.) improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and effectively depletes leukemia-initiating cells. [1]For the detailed information of STF-118804, the solubility of STF-118804 in water, the solubility of STF-118804 in DMSO, the solubility of STF-118804 in PBS buffer, the animal experiment (test) of STF-118804, the cell expriment (test) of STF-118804, the in vivo, in vitro and clinical trial test of STF-118804, the EC50, IC50,and Affinity of STF-118804, Please contact DC Chemicals.
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