CH-223191 supplier|CH223191|DC Chemicals
DC Chemicals provides CH-223191, other names: CH223191，CH 223191, cas: 301326-22-7. In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
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CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.
CH-223191, other names: CH223191，CH 223191, cas: 301326-22-7, Molecule formular: C19H19N5O, Molecule Weight: 333.39, Chemical name: 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
CH-223191 preferentially inhibits the ability of some classes of AhR agonists (2,3,7,8-tetrachlorodibenzo-p-dioxin and related HAHs), but not others (PAHs, flavonoids, or indirubin), to bind to and/or activate the AhR and AhR signal transduction [1]. CH-223191 potently inhibits TCDD-induced AhR-dependent transcription. In addition, CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR For the detailed information of CH-223191, the solubility of CH-223191 in water, the solubility of CH-223191 in DMSO, the solubility of CH-223191 in PBS buffer, the animal experiment (test) of CH-223191, the cell expriment (test) of CH-223191, the in vivo, in vitro and clinical trial test of CH-223191, the EC50, IC50,and affinity,of CH-223191, Please contact DC Chemicals.
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