Glutaminase Inhibitor II, BPTES supplier||DC Chemicals
DC Chemicals provides Glutaminase Inhibitor II, BPTES, other names: , cas: 314045-39-1. In stock.
Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643281；
BPTES is a selective inhibitor of Glutaminase GLS1 (KGA)
Glutaminase Inhibitor II, BPTES, other names: , cas: 314045-39-1, Molecule formular: C24H24N6O2S3
, Molecule Weight: 524.68, Chemical name: Bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide
BPTES is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. Glutaminase converts glutamine to glutamate, which is an important excitatory neurotransmitter in brain and can be further oxidized to α-ketoglutarate to feed the tricarboxylic acid (TCA) cycle and to glutathione, which is important for controlling the level of reactive oxygen species (ROS), particularly important for cancer cell growth. BPTES was found to slow growth of glioma cells. BPTES is a noncompetitive inhibitor with a Ki of 3 μM. For the detailed information of Glutaminase Inhibitor II, BPTES, the solubility of Glutaminase Inhibitor II, BPTES in water, the solubility of Glutaminase Inhibitor II, BPTES in DMSO, the solubility of Glutaminase Inhibitor II, BPTES in PBS buffer, the animal experiment (test) of Glutaminase Inhibitor II, BPTES, the cell expriment (test) of Glutaminase Inhibitor II, BPTES, the in vivo, in vitro and clinical trial test of Glutaminase Inhibitor II, BPTES, the EC50, IC50,and affinity,of Glutaminase Inhibitor II, BPTES, Please contact DC Chemicals.
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