DC Chemicals supplies: Bioymifi,cas: 1420071-30-2,Catalog: DC7603,In stock.
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Product name: Bioymifi, Synonyms: (DR5 Activator), cas: 1420071-30-2, MW: 494.32, Molecule Formula: C22H12BrN3O4S
Bioymifi, cas 1420071-30-2, Purity>98%, In stock,from DC Chemicals. Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells.Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. IC50 value: Target: In comparison with A2C2, bioymifi was able to promote cell death without the need for the Smac mimetic in T98G cells. Notably, at a 10-μM concentration, bioymifi induced processing of caspase-3 into smaller fragments. Z-VAD inhibited these caspase-mediated cleavages. caspase-3 was rapidly activated as early as 2 h after bioymifi treatment of T98G cells. The caspase-3 activity was markedly increased after 8 h of treatment. Bioymifi induces caspase-8–dependent apoptosis.
Bioymifi(DR5 Activator) is the first novel and potent small-molecule activatior of the TRAIL receptor DR5 in human cancer cells. IC50 value: Target: In comparison with A2C2, bioymifi was able to promote cell death without the need For the Smac mimetic in T98G cells. Notably, at a 10-μM concentration, bioymifi induced processing of caspase-3 into smaller fragments. Z-VAD inhibited these caspase-mediated cleavages. caspase-3 was rapidly activated as early as 2 h after bioymifi treatment of T98G cells. The caspase-3 activity was markedly increased after 8 h of treatment. Bioymifi induces caspase-8–dependent apoptosis.For the detailed information of Bioymifi, the solubility of Bioymifi in water, the solubility of Bioymifi in DMSO, the solubility of Bioymifi in PBS buffer, the animal experiment (test) of Bioymifi, the cell expriment (test) of Bioymifi, the in vivo, in vitro and clinical trial test of Bioymifi, the EC50, IC50,and Affinity of Bioymifi, Please contact DC Chemicals.
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