2015年3月31日星期二

L-006,235 supplier|L-006235|DC Chemicals

L-006,235 supplier|L-006235|DC Chemicals
DC Chemicals provides L-006,235, other names: L-006235, cas: 294623-49-7. In stock.

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-58447131;Fax:+86-21-61643264;

L 006235 is a reversible and potent cathepsin K inhibitor that displays more than a 4000 fold selectivity over cathepsins B, L and S.

L-006,235, other names: L-006235, cas: 294623-49-7, Molecule formular: , Molecule Weight: , Chemical name: N-[1-[[(Cyanomethyl)amino]carbonyl] cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazo lyl]benzamide

L-006,235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S. Displays reduced selectivity in cell-based assays possibly due to lysosomal accumulation. Reduces collagen breakdown and promotes bone deposition in vivo. Orally active and has intrinsic fluorescence. For the detailed information of L-006,235, the solubility of L-006,235 in water, the solubility of L-006,235 in DMSO, the solubility of L-006,235 in PBS buffer, the animal experiment (test) of  L-006,235, the cell expriment (test) of L-006,235, the in vivo, in vitro and clinical trial test of L-006,235, the EC50, IC50,and affinity,of L-006,235, Please contact DC Chemicals.

没有评论:

发表评论