DC Chemicals supplies: APD668,cas: 832714-46-2,Catalog: DC7655,In stock.
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Product name: APD668, Synonyms: APD 668; APD-668, cas: 832714-46-2, MW: 477.51, Molecule Formula: C21H24FN5O5S
APD668, cas: 832714-46-2, From DC Chemicals. APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM For hGPR119 and ratGPR119 respectively.
IC50 value: 2.7 nM (EC50) [1]
Target: GPR119
Chronic treatment withAPD668 showed For the first time that blood glucose and glycated hemoglobin (HbA1c) levels could be significantly reduced in Zucker Diabetic Fatty (ZDF) rats over several weeks of dosing. APD668 was the ?rst compound with this mechanism of action to be progressed into clinical development For the treatment of diabetes.
For the detailed information of APD668, the solubility of APD668 in water, the solubility of APD668 in DMSO, the solubility of APD668 in PBS buffer, the animal experiment (test) of APD668, the cell expriment (test) of APD668, the in vivo, in vitro and clinical trial test of APD668, the EC50, IC50,and Affinity of APD668, Please contact DC Chemicals.
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