DC Chemicals supplies: Splitomicin ,cas: CAS Number 5690-03-9,Catalog: DC7673,In stock.
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Product name: Splitomicin , Synonyms: , cas: CAS Number 5690-03-9, MW: 198.22, Molecule Formula: C13H10O2
Splitomicin , cas: CAS Number 5690-03-9, , Purity:>98%. Best Price and high quality from DC Chemicals. Splitomicin is a derivative of β-naphthol is an inhibitor of Silent Information Regulator 2 (SIR2).
Splitomicin, a derivative of β-naphthol is an inhibitor of Silent information Regulator 2 (SIR2). It inhibits the NAD+-dependent deacetylase activity of Sir2 in vitro.5 It increases the levels of cyclic AMP by inhibiting the activity of cyclic AMP phosphodiesterase, interferes with mobilization of intracellular Ca+2 and ATP release. This results in inhibition of platelet aggregation that is effective in cardiovascular and cerebrovascular diseases.6 Splitomicin was used to inhibit SIRT1 in human aortic endothelial cells1,2 and sirtuins in human breast cancer cells.3 Mouse leukaemic monocyte macrophage cell line was treated with Splitomicin prior to cholesterol efflux studies.4For the detailed information of Splitomicin , the solubility of Splitomicin in water, the solubility of Splitomicin in DMSO, the solubility of Splitomicin in PBS buffer, the animal experiment (test) of Splitomicin , the cell expriment (test) of Splitomicin , the in vivo, in vitro and clinical trial test of Splitomicin , the EC50, IC50,and Affinity of Splitomicin , Please contact DC Chemicals.
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