CA-074-Me||buy from supplier D&C Chemicals

CA-074-Me||buy from supplier D&C Chemicals

DC Chemicals supplies: CA-074-Me,cas: 147859-80-1,Catalog: DC7697,In stock.

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Product name: CA-074-Me, Synonyms: CA-074 Me , cas: 147859-80-1, MW: 397.5, Molecule Formula: C19H31N3O6

CA-074-Me, purity: >98%, Best price from D&C Chemicals. CA-074 Me is a selective and cell-permeable inhibitor of cathepsin B.

CA-074 Me is a membrane-permeable and selective inhibitor of cathepsin B with IC50 value of 36.3 nM [1, 2].

CA-074 Me is a methyl ester derivative of CA-074. In cultured human gingival fibroblasts, CA-074 Me exerted a 95% inhibition of cathepsin B and partial inhibition (54%) of the combined activities of cathepsins B and L. CA-074 Me was also found to inhibit cathespin L under reducing conditions. It inhibited the activity of purified human cathepsin L by more than 90% when the enzyme had been pre-incubated with 1.4 mM DTT or 4.2 mM GSH for 2 hours. Besides that, CA-074 Me completely inhibited cathepsin B in the presence of 1.4 mM DTT [2, 3].For the detailed information about the solubility of CA-074 Me  in water, the solubility of CA-074 Me  in DMSO, the solubility of CA-074 Me  in PBS buffer, the animal experiment of CA-074 Me ,the in vivo and in vitro test of CA-074 Me ,the cell experiment of CA-074 Me ,the IC50 and EC50 of CA-074 Me  please contact DC Chemicals.