DC Chemicals supplies: Mps1-IN-3,cas: 1125593-20-5 ,Catalog: DC7706,In stock.
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Product name: Mps1-IN-3, Synonyms: MPS1 INHIBITOR, Mps1-IN3, cas: 1125593-20-5 , MW: 537.63, Molecule Formula: C26H31N7O4S
Mps1-IN-3, cas: 1125593-20-5 , purity>98, from DC Chemicals. Mps1-IN-3 is an inhibitor of Monopolar spindle 1 (MPS1, also known as TTK), a Dual-specificity kinase required for spindle pole body duplication and spindle checkpoint function.
Mps1-IN-3 is an inhibitor of Monopolar spindle 1 (MPS1, also known as TTK), a Dual-specificity kinase required for spindle pole body duplication and spindle checkpoint function. Mps1-IN-3 inhibited Mps1 kinase activity with an IC50 value of 50 nM inhibited the proliferation of U251 glioblastoma cells as determined by cell counting with an IC50 value of approximately 5 μM, and sensitized glioblastoma cells to vincristine in orthotopic mouse models. For the detailed information about the solubility of Mps1-IN-3 in water, the solubility of Mps1-IN-3 in DMSO, the solubility of Mps1-IN-3 in PBS buffer, the animal experiment of Mps1-IN-3 ,the in vivo and in vitro test of Mps1-IN-3 ,the cell experiment of Mps1-IN-3 ,the IC50 and EC50 of Mps1-IN-3 please contact DC Chemicals.
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