PF 1022A|PF1022A|buy from supplier D&C Chemicals

PF 1022A|PF1022A|buy from supplier D&C Chemicals

DC Chemicals supplies: PF 1022A,cas: 133413-70-4,Catalog: DC7691,In stock.

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Product name: PF 1022A, Synonyms: PF1022A; PF-1022A, cas: 133413-70-4, MW: 949.18, Molecule Formula: C52H76N4O12

PF 1022A, purity: >98%, Best price from D&C Chemicals. PF 1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties; acts as an ionophore.

PF 1022A is a N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties; acts as an ionophore.

IC50 value:

Target:

PF 1022A showed strong anthelmintic activities against Ascaridia galli in chickens [1]. PF1022A is a novel anthelmintic that binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes. Furthermore, PF1022A binds to GABA receptors, which might contribute to the anthelmintic effect. Like other cyclodepsipeptides, PF1022A acts as an ionophore [2].  In vitro, PF1022A showed low activity on embryonation but significantly inhibited egg hatch (10 and 100 μg/ml), whereas albendazole (10 and 100 μg/ml) revealed statistically significant inhibitions of both embryonation and egg hatch. PF1022A (1-100 μg/ml) completely inhibited larval movement at most examination points [3].For the detailed information about the solubility of PF 1022A in water, the solubility of PF 1022A in DMSO, the solubility of PF 1022A in PBS buffer, the animal experiment of PF 1022A,the in vivo and in vitro test of PF 1022A,the cell experiment of PF 1022A,the IC50 and EC50 of PF 1022A please contact DC Chemicals.