DC Chemicals supplies: MG-101,cas: 110044-82-1,Catalog: DC7702,In stock.
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Product name: MG-101, Synonyms: Calpain inhibitor-1, cas: 110044-82-1, MW: 383.53, Molecule Formula: C20H37N3O4
MG-101, cas: 110044-82-1, purity>98, from DC Chemicals. MG-101 is a calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines.
Calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro. Also attenuates ischemia/reperfusion injury in cardiomyocytes, hepatocytes and renal tubular cells through downregulation of iNOS and COX-2 expression. For the detailed information about the solubility of MG-101 in water, the solubility of MG-101 in DMSO, the solubility of MG-101 in PBS buffer, the animal experiment of MG-101 ,the in vivo and in vitro test of MG-101 ,the cell experiment of MG-101 ,the IC50 and EC50 of MG-101 please contact DC Chemicals.
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