DC Chemicals supplies: AEBSF-hydrochloride,cas: 30827-99-7,Catalog: DC7703,In stock.
Contact: website: www.dcchemicals.com,
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Product name: AEBSF-hydrochloride, Synonyms: , cas: 30827-99-7, MW: 239.69, Molecule Formula: C8H11ClFNO2S
AEBSF-hydrochloride, cas: 30827-99-7, purity>98, from DC Chemicals. AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor.
AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural. [1] AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β. [2] AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern. [4] AEBSF (76.8 mg/kg daily i.p.) results in prolongation of the survival of mice that have been given a lethal T. gondii infection. [3] AEBSF also reduces airway response and underlying inflammation in cockroach allergen-induced murine model. [4] For the detailed information about the solubility of AEBSF-hydrochloride in water, the solubility of AEBSF-hydrochloride in DMSO, the solubility of AEBSF-hydrochloride in PBS buffer, the animal experiment of AEBSF-hydrochloride ,the in vivo and in vitro test of AEBSF-hydrochloride ,the cell experiment of AEBSF-hydrochloride ,the IC50 and EC50 of AEBSF-hydrochloride please contact DC Chemicals.
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