XL388 |cas 1251156-08-7 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: XL388,cas 1251156-08-7, Cat No. DC3123, In stock

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Product name: XL388, Synonym:　XL-388,XL 388, Cat No. DC3123, Cas: 1251156-08-7, Chemical Name:N/A, Molecular Formula: C23H22FN3O4S, MW: 455.5

XL388 Cas#1251156-08-7.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR).

Description of XL388: XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR). XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-BP1) and mTOR complex 2 (pAKT (S473)) substrates. XL388 displayed good pharmacokinetics and oral exposure in multiple species with moderate bioavailability. Oral administration of XL388 to athymic nude mice implanted with human tumor xenografts afforded significant and dose-dependent antitumor activity.

For the detailed information about the solubility of XL388 in water, the solubility of XL388 in DMSO, the solubility of XL388 in PBS buffer, the animal experiment of XL388,the in vivo and in vitro test of XL388,the cell experiment of XL388,the IC50 and EC50 of XL388please contact DC Chemicals.