2014年4月20日星期日

Vandetanib |cas 443913-73-3(338992-00-0) |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply:Vandetanib ,cas 443913-73-3(338992-00-0), Cat No. DC3134, In stock

Contact: website: www.dcchemicals.com,
sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,
Tel: +86-21-61454686;Fax:+86-21-61642641;

Product name: Vandetanib (ZD6474), Synonym: ZD6474,AZD-6474, Cat No. DC3134, Cas: 443913-73-3(338992-00-0), Chemical Name:N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine, Molecular Formula: C22H24BrFN4O2, MW: 475.35

Vandetanib (ZD6474) Cas#443913-73-3(338992-00-0).Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Vandetanib (Zactima, ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM.

Vandetanib is an orally bioavailable 4-anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF-stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell proliferation and migration and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
For the detailed information about the solubility of Vandetanib in water, the solubility of Vandetanib in DMSO, the solubility of Vandetanib in PBS buffer, the animal experiment of Vandetanib,the in vivo and in vitro test of Vandetanib,the cell experiment of Vandetanib,the IC50 and EC50 of Vandetanibplease contact DC Chemicals.

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