GSK690693 |cas 937174-76-0 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: GSK690693 ,cas 937174-76-0, Cat No. DC2070, In stock

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Product name: GSK-690693, Synonym:　GSK690693, GSK 690693, Cat No. DC2070, Cas: 937174-76-0, Chemical Name:4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((S)-piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol, Molecular Formula: C21H27N7O3, MW: 425.48

GSK-690693 Cas#937174-76-0.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! GSK690693 is a pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 2 nM, 13 nM, and 9 nM, respectively.

GSK690693 is a pan-AKT kinase inhibitor, is also an aminofurazan-derived inhibitor of Akt kinases with potential antineoplastic activity. Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, which may result in the inhibition of protein phosphorylation events downstream from Akt kinases in the PI3K/Akt signaling pathway, and, subsequently, the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. In addition, this agent may inhibit other protein kinases including protein kinase C (PKC) and protein kinase A (PKA). As serine/threonine protein kinases which are involved in a number of biological processes, AKT kinases promote cell survival by inhibiting apoptosis and are required for glucose transport. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of GSK690693 in water, the solubility of GSK690693 in DMSO, the solubility of GSK690693 in PBS buffer, the animal experiment of GSK690693,the in vivo and in vitro test of GSK690693,the cell experiment of GSK690693,the IC50 and EC50 of GSK690693please contact DC Chemicals.