Necrostatin-1 |cas 4311-88-0 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Necrostatin-1 ,cas 4311-88-0, Cat No. DC2084, In stock

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Product name: Necrostatin-1, Synonym:　Necrostatin1, Necrostatin 1, Cat No. DC2084, Cas: 4311-88-0, Chemical Name:4-Imidazolidinone, 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-, Molecular Formula: C13H13N3OS, MW: 259.33

Necrostatin-1 Cas#4311-88-0.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.

Necrostatin-1 is an inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.

For the detailed information about the solubility of Necrostatin-1 in water, the solubility of Necrostatin-1 in DMSO, the solubility of Necrostatin-1 in PBS buffer, the animal experiment of Necrostatin-1,the in vivo and in vitro test of Necrostatin-1,the cell experiment of Necrostatin-1,the IC50 and EC50 of Necrostatin-1please contact DC Chemicals.