CYT387 (CYT-387) |cas 1056634-68-4 |Supplier|Price|Buy

DC Chemicals Supply: CYT387 (CYT-387) ,cas 1056634-68-4, Cat No. DC3107, In stock

Contact: website: www.dcchemicals.com,

sales@dcchemicals.com,order@dcchemicals.com,info@dcchemicals.com,

Tel: +86-21-61454686;Fax:+86-21-61642621；

Product name: CYT387 (CYT-387), Synonym:　CYT 11387,CYT387 (CYT 387), Cat No. DC3107, Cas: 1056634-68-4, Chemical Name:N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide, Molecular Formula: C23H22N6O2, MW: 414.46

CYT387 (CYT-387) Cas#1056634-68-4.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 nM and 18 nM, respectively.

CYT387 is an orally-administered, potent, selective inhibitor of the JAK1 and JAK2 kinases, enzymes which have been implicated in a number of disorders including myeloproliferative neoplasms (MPNs), inflammatory diseases and certain cancers. The molecule possesses an excellent selectivity and safety profile with minimal off-target activity, a favorable pharmacokinetic and toxicological profile, and the prospect of limited drug/drug interactions. Data from MPN patient samples demonstrate suppression of JAK enzyme over-activity. CYT387 was developed by Australian biotech company Cytopia Research Pty Ltd, and is now part of the YM BioSciences development program. [source: http://www.ymbiosciences.com].

For the detailed information about the solubility of CYT387 (CYT-387) in water, the solubility of CYT387 (CYT-387) in DMSO, the solubility of CYT387 (CYT-387) in PBS buffer, the animal experiment of CYT387 (CYT-387),the in vivo and in vitro test of CYT387 (CYT-387),the cell experiment of CYT387 (CYT-387),the IC50 and EC50 of CYT387 (CYT-387)please contact DC Chemicals.