Brefeldin A |cas 20350-15-6 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Brefeldin A  ,cas 20350-15-6, Cat No. DC2091, In stock

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Product name: Brefeldin A, Synonym:　BFA, Cat No. DC2091, Cas: 20350-15-6, Chemical Name:4H-Cyclopent[f]oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-, (1R,2E,6S,10E,11aS,13S,14aR)-, Molecular Formula: C16H24O4, MW: 280.36

BrefeldinA Cas#20350-15-6.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells.

Brefeldin A (BFA) is a fungal metabolite 

demonstrated to reversibly interfere with anterograde 

transport from the endoplasmic reticulum to the Golgi 

apparatus . While initially isolated as an antibiotic 

, and does have a wide range of antibiotic activity, it is 

primarily used as a biological research tool for studying protein transport. Treatment leads to a rapid accumulation of proteins within the ER and collapse of the Golgi stacks. Treatment with BFA can also inhibit protein secretion and prolonged exposure can induce apoptosis . The main target of BFA appears to be ADP-ribosylation factor (ARF), which is responsible for association of coat protein to the Golgi membrane . For the detailed information about the solubility of Brefeldin A  in water, the solubility of Brefeldin A  in DMSO, the solubility of Brefeldin A  in PBS buffer, the animal experiment of Brefeldin A ,the in vivo and in vitro test of Brefeldin A ,the cell experiment of Brefeldin A ,the IC50 and EC50 of Brefeldin A please contact DC Chemicals.