TMS |cas 24144-92-1 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: TMS  ,cas 24144-92-1, Cat No. DC2080, In stock

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Product name: TMS, Synonym:　N/A, Cat No. DC2080, Cas: 24144-92-1, Chemical Name:N/A, Molecular Formula: C18H20O4, MW: 300.35

TMS Cas#24144-92-1.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.

CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids; eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.1 It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making it a useful tool to differentiate between various CYP450 families.1 In cultured human colon cancer cells, TMS induces apoptosis and inhibits cell growth with an IC50 of 0.8 ?g/ml.2

For the detailed information about the solubility of TMS  in water, the solubility of TMS  in DMSO, the solubility of TMS  in PBS buffer, the animal experiment of TMS ,the in vivo and in vitro test of TMS ,the cell experiment of TMS ,the IC50 and EC50 of TMS please contact DC Chemicals.