DC Chemicals Supply: Apoptosis Activator 2 ,cas 79183-19-0, Cat No. DC2066, In stock
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Product name: Apoptosis Activator 2, Synonym: N/A, Cat No. DC2066, Cas: 79183-19-0, Chemical Name:1-(3,4-DICHLOROBENZYL)-1H-INDOLE-2,3-DIONE, Molecular Formula: C15H9Cl2NO2, MW: 306.14
Apoptosis Activator 2 Cas#79183-19-0.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.
Apoptosis Activator 2 is a cell-permeable indoledione compound that activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells by promoting the oligomerization of Apaf-1 into the mature apoptosome. Its cytotoxicity is selective towards tumor cells (IC50 < 10 μM for Jurkat, Molt-4, and CCRF-CEM). Apoptosis Activator 2 shows little or no effect on non-tumor cells or cells that are deficient in caspase-3 or Apaf-1. Apoptosis Activator 2 is an activator of caspase-3.
For the detailed information about the solubility of Apoptosis Activator 2 in water, the solubility of Apoptosis Activator 2 in DMSO, the solubility of Apoptosis Activator 2 in PBS buffer, the animal experiment of Apoptosis Activator 2 ,the in vivo and in vitro test of Apoptosis Activator 2 ,the cell experiment of Apoptosis Activator 2 ,the IC50 and EC50 of Apoptosis Activator 2 please contact DC Chemicals.
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