Imatinib (STI571) |cas 152459-95-9 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Imatinib (STI571) ,cas 152459-95-9, Cat No. DC2104, In stock

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Product name: Imatinib (STI571), Synonym:　STI-571, Cat No. DC2104, Cas: 152459-95-9, Chemical Name:N/A, Molecular Formula: C29H31N7O, MW: 493.6

Imatinib (STI571) Cas#152459-95-9.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

Imatinib mesylate is a small molecule that inhibits the c-Abl protein-tyrosine kinase, a kinase specifically important for proliferation of chronic myelogenous leukemia (CML). A translocation event between chromosomes 9 and 22 generates the Philadelphia chromosome, which then produces the Bcr-Abl fusion protein with aberrant kinase activity that promotes rapid cell proliferation. Imatinib binds up this crucial kinase, halting CML related growth. Imatinib mesylate has further been displayed to inhibit PDGFR and tyrosine kinases associated with c-Kit.For the detailed information about the solubility of Imatinib (STI571) in water, the solubility of Imatinib (STI571) in DMSO, the solubility of Imatinib (STI571) in PBS buffer, the animal experiment of Imatinib (STI571),the in vivo and in vitro test of Imatinib (STI571),the cell experiment of Imatinib (STI571),the IC50 and EC50 of Imatinib (STI571)please contact DC Chemicals.