NVP-BGT226 (BGT226） |cas 1245537-68-1 |Supplier|Price|Buy

DC Chemicals Supply: NVP-BGT226 (BGT226） ,cas 1245537-68-1, Cat No. DC3133, In stock

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Product name: NVP-BGT226 (BGT226）, Synonym:　BGT-226,NVP BGT226 (BGT226）, Cat No. DC3133, Cas: 1245537-68-1, Chemical Name:8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one Maleic acid, Molecular Formula: C28H25F3N6O2.C4H4O4, MW: 650.6

NVP-BGT226 (BGT226） Cas#1245537-68-1.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! NVP-BGT226 is a novel dual PI3K/mTOR inhibitor with IC50 of 1 nM.

Description of BGT226: BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability; apoptotic cell death may ensue. Bax is a member of the proapoptotic Bcl2 family of proteins. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of NVP-BGT226 (BGT226） in water, the solubility of NVP-BGT226 (BGT226） in DMSO, the solubility of NVP-BGT226 (BGT226） in PBS buffer, the animal experiment of NVP-BGT226 (BGT226）,the in vivo and in vitro test of NVP-BGT226 (BGT226）,the cell experiment of NVP-BGT226 (BGT226）,the IC50 and EC50 of NVP-BGT226 (BGT226）please contact DC Chemicals.