17-DMAG (Alvespimycin) |cas 467214-20-6 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: 17-DMAG (Alvespimycin) ,cas 467214-20-6, Cat No. DC2074, In stock

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Product name: 17-DMAG (Alvespimycin), Synonym:　17DMAG, 17 DMAG, Cat No. DC2074, Cas: 467214-20-6, Chemical Name:N/A, Molecular Formula: C32H48N4O8.HCl, MW: 616.75

17-DMAG (Alvespimycin) Cas#467214-20-6.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! 17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM.

Alvespimycin hydrochloride is the hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to HSP90, a chaperone protein that aids in the assembly, maturation and folding of proteins. Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of 17-DMAG (Alvespimycin) in water, the solubility of 17-DMAG (Alvespimycin) in DMSO, the solubility of 17-DMAG (Alvespimycin) in PBS buffer, the animal experiment of 17-DMAG (Alvespimycin),the in vivo and in vitro test of 17-DMAG (Alvespimycin),the cell experiment of 17-DMAG (Alvespimycin),the IC50 and EC50 of 17-DMAG (Alvespimycin)please contact DC Chemicals.