VX-680 (MK-0457, Tozasertib) |cas 639089-54-6 |Supplier|Price|Buy

DC Chemicals Supply: VX-680 (MK-0457, Tozasertib) ,cas 639089-54-6, Cat No. DC3106, In stock

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Product name: VX-680 (MK-0457,Tozasertib), Synonym:　VX680,MK0457,VX 680 (MK 0457,Tozasertib), Cat No. DC3106, Cas: 639089-54-6, Chemical Name:N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide, Molecular Formula: C23H28N8OS, MW: 464.59

VX-680 (MK-0457,Tozasertib) Cas#639089-54-6.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! VX-680 (MK-0457, Tozasertib) is a pan-Aurora inhibitor of Aurora A, Aurora B and Aurora C with Kiapp of 0.6 nM, 18 nM and 4.6 nM, respectively.

Tozasertib lactate is the lactate salt of tozasertib, a synthetic, small-molecule Aurora kinase inhibitor with potential antitumor activity. Tozasertib binds to and inhibits Aurora kinases (AKs), thereby inducing apoptosis in tumor cells in which AKs are overexpressed. AKs, a family of serine-threonine kinases, are essential for mitotic progression, spindle formation, centrosome maturation, chromosomal segregation, and cytokinesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of VX-680 (MK-0457, Tozasertib) in water, the solubility of VX-680 (MK-0457, Tozasertib) in DMSO, the solubility of VX-680 (MK-0457, Tozasertib) in PBS buffer, the animal experiment of VX-680 (MK-0457, Tozasertib),the in vivo and in vitro test of VX-680 (MK-0457, Tozasertib),the cell experiment of VX-680 (MK-0457, Tozasertib),the IC50 and EC50 of VX-680 (MK-0457, Tozasertib)please contact DC Chemicals.