DC Chemicals Supply: Okadaic acid ,cas 78111-17-8, Cat No. DC2075, In stock
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Product name: Okadaic acid, Synonym: N/A, Cat No. DC2075, Cas: 78111-17-8, Chemical Name:N/A, Molecular Formula: C44H68O13, MW: 805
Okadaic acid Cas#78111-17-8.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Okadaic Acid is a potent inhibitor of PP1 and PP2A phosphatases
Okadaic acid is a naturally occurring polyether toxin that was originally derived from marine dinoflagellates, Prorocentrium spp.. It is a reversible, potent and selective inhibitor of two serine threonine protein phosphatases: PP2A-C (PP2A) which is inhibited completely at 1 nM and PP1 which is inhibited at higher concentrations (IC50= 10-15 nM). PP2B is much less sensitive to okadaic acid than PP1, while PP2C is not inhibited. This selectivity is the basis for an improved identification and quantification procedure for these enzymes. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctions, causes vasodilation and is a very potent tumor promoter. Okadaic acid is an extremely useful tool for studying cellular processes that are regulated by phosphorylation. Okadaic Acid is an activator of PKC.
For the detailed information about the solubility of Okadaic acid in water, the solubility of Okadaic acid in DMSO, the solubility of Okadaic acid in PBS buffer, the animal experiment of Okadaic acid ,the in vivo and in vitro test of Okadaic acid ,the cell experiment of Okadaic acid ,the IC50 and EC50 of Okadaic acid please contact DC Chemicals.
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