17-AAG |cas 75747-14-7 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: 17-AAG ,cas 75747-14-7, Cat No. DC2073, In stock

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Product name: 17-AAG, Synonym:　17AAG, 17 AAG, Cat No. DC2073, Cas: 75747-14-7, Chemical Name:Geldanamycin, 17-demethoxy-17-(2-propenylamino)-, Molecular Formula: C31H43N3O8, MW: 585.69

17-AAG Cas#75747-14-7.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! 17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50of 5 nM.

Telatinib (17-AGG) is an orally bioavailable, small-molecule inhibitor of several receptor protein tyrosine kinases with potential antiangiogenic and antineoplastic activities. Telatinib binds to and inhibits the vascular endothelial growth factor receptors (VEGFRs) type 2 and 3, platelet-derived growth factor receptor beta (PDGFRb) and c-Kit, which may result in the inhibition of angiogenesis and cellular proliferation in tumors in which these receptors are upregulated. These telatinib-inhibited receptor protein tyrosine kinases are overexpressed or mutated in many tumor cell types and may play key roles in tumor angiogenesis and tumor cell proliferation. 17-AAG is a synthetic analogue of the benzoquinone ansamycin antibiotic geldanamycin and has also been found to inhibit the molecular chaperone Hsp90. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). 

For the detailed information about the solubility of 17-AAG in water, the solubility of 17-AAG in DMSO, the solubility of 17-AAG in PBS buffer, the animal experiment of 17-AAG,the in vivo and in vitro test of 17-AAG,the cell experiment of 17-AAG,the IC50 and EC50 of 17-AAGplease contact DC Chemicals.