BMS 754807 |cas 1001350-96-4, |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: BMS 754807 ,cas 1001350-96-4,, Cat No. DC3126, In stock

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Product name: BMS754807, Synonym:　BMS-754807,BMS 754807, Cat No. DC3126, Cas: 1001350-96-4,, Chemical Name:(S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide, Molecular Formula: C23H24FN9O, MW: 461.49

BMS754807 Cas#1001350-96-4,.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! BMS-754807 is a potent and reversible inhibitor of IGF-1R/IR family kinases, inhibits IGF-1R, IR, Met, TrkA and TrkB with IC50 of 1.8 nM, 1.7 nM, 5.6 nM, 7.4 nM and 4.1 nM, respectively.

BMS-754807 is an orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity. IGF-1R antagonist BMS-7548077 binds to IGF-1R, preventing IGF-1 ligand binding and activation of IGF-1R-mediated signaling pathways; inhibition of IGF-1R-mediated signaling pathways may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-1R is a receptor tyrosine kinase expressed on most tumor cells and is involved in mitogenesis, angiogenesis, and tumor cell survival. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

For the detailed information about the solubility of BMS 754807 in water, the solubility of BMS 754807 in DMSO, the solubility of BMS 754807 in PBS buffer, the animal experiment of BMS 754807,the in vivo and in vitro test of BMS 754807,the cell experiment of BMS 754807,the IC50 and EC50 of BMS 754807please contact DC Chemicals.