PF-04971729 (Ertugliflozin) |cas 1210344-57-2 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: PF-04971729 (Ertugliflozin) ,cas 1210344-57-2, Cat No. DC3108, In stock

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Product name: PF-04971729 (Ertugliflozin), Synonym:　PF04971729,PF 04971729 (Ertugliflozin), Cat No. DC3108, Cas: 1210344-57-2, Chemical Name:N/A, Molecular Formula: C22H25ClO7, MW: 436.9

PF-04971729 (Ertugliflozin) Cas#1210344-57-2.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! PF-04971729 is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus.

PF-04971729, a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2, is currently in phase 2 trials for the treatment of diabetes mellitus. Inhibitory effects against the organic cation transporter 2-mediated uptake of [14C]metformin by PF-04971729 also were very weak (IC50 900μM).The disposition of PF-04971729, an orally active selective inhibitor of the sodium-dependent glucose cotransporter 2, was studied after a single 25-mg oral dose of [14C]-PF-04971729 to healthy human subjects. The absorption of PF-04971729 in humans was rapid with a Tmax at ~ 1.0 h. Of the total radioactivity excreted in feces and urine, unchanged PF-04971729 collectively accounted for ~ 35.3% of the dose, suggestive of moderate metabolic elimination in humans.

For the detailed information about the solubility of PF-04971729 (Ertugliflozin) in water, the solubility of PF-04971729 (Ertugliflozin) in DMSO, the solubility of PF-04971729 (Ertugliflozin) in PBS buffer, the animal experiment of PF-04971729 (Ertugliflozin),the in vivo and in vitro test of PF-04971729 (Ertugliflozin),the cell experiment of PF-04971729 (Ertugliflozin),the IC50 and EC50 of PF-04971729 (Ertugliflozin)please contact DC Chemicals.