Gemcitabine HCl (Gemzar, LY188011) |cas 122111-03-9 |Supplier|Price|Buy

DC Chemicals Supply: Gemcitabine HCl (Gemzar, LY188011) ,cas 122111-03-9, Cat No. DC2107, In stock

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Product name: Gemcitabine HCl (Gemzar,LY188011), Synonym:　LY-188011, Cat No. DC2107, Cas: 122111-03-9, Chemical Name:4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride, Molecular Formula: C9H11F2N3O4.HCI, MW: 299.66

Gemcitabine HCl (Gemzar,LY188011) Cas#122111-03-9.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Gemcitabine Hydrochloride (Gemzar) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

Gemcitabine hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

For the detailed information about the solubility of Gemcitabine HCl (Gemzar, LY188011) in water, the solubility of Gemcitabine HCl (Gemzar, LY188011) in DMSO, the solubility of Gemcitabine HCl (Gemzar, LY188011) in PBS buffer, the animal experiment of Gemcitabine HCl (Gemzar, LY188011),the in vivo and in vitro test of Gemcitabine HCl (Gemzar, LY188011),the cell experiment of Gemcitabine HCl (Gemzar, LY188011),the IC50 and EC50 of Gemcitabine HCl (Gemzar, LY188011)please contact DC Chemicals.