TPEN |cas 16858-02-9 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: TPEN  ,cas 16858-02-9, Cat No. DC2081, In stock

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Product name: TPEN, Synonym:　N/A, Cat No. DC2081, Cas: 16858-02-9, Chemical Name:N/A, Molecular Formula: C26H28N6, MW: 424.54

TPEN Cas#16858-02-9.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! TPEN is a cell permeable, high-affinity heavy metal (Zn2+>Fe2+>Mn2+) chelator that exhibits low affinity for Mg2+ and Ca2+.

TPEN is a cell permeable, high-affinity heavy metal (Zn2+>Fe2+>Mn2+) chelator that exhibits low affinity for Mg2+ and Ca2+. The compound is lipid-soluble and has been shown to permeate artificial and natural membranes. Research shows that TPEN induces apoptosis in human and rat thymocytes through DNA fragmentation and Caspace-3 activation. TPEN also induces mitochondrial cytochrome C translocation to the cytosol in human PBL. A recent study has proved this chelator to work in conjunction with the fluorescent probe Fura-2 (sc-202163) in biophysical studies of Ca2+.

For the detailed information about the solubility of TPEN  in water, the solubility of TPEN  in DMSO, the solubility of TPEN  in PBS buffer, the animal experiment of TPEN ,the in vivo and in vitro test of TPEN ,the cell experiment of TPEN ,the IC50 and EC50 of TPEN please contact DC Chemicals.