GDC-0068 |cas 1001264-89-6 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: GDC-0068 ,cas 1001264-89-6, Cat No. DC3109, In stock

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Product name: GDC-0068, Synonym:　GDC0068,GDC 0068, Cat No. DC3109, Cas: 1001264-89-6, Chemical Name:(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one, Molecular Formula: C24H32ClN5O2, MW: 458

GDC-0068 Cas#1001264-89-6.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.

Description of GDC-0068: GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

For the detailed information about the solubility of GDC-0068 in water, the solubility of GDC-0068 in DMSO, the solubility of GDC-0068 in PBS buffer, the animal experiment of GDC-0068,the in vivo and in vitro test of GDC-0068,the cell experiment of GDC-0068,the IC50 and EC50 of GDC-0068please contact DC Chemicals.