2015年10月25日星期日

Tizoxanide|inhibitor of hepatitis B virus and hepatitis C virus

Tizoxanide|inhibitor of hepatitis B virus and hepatitis C virus cas: 173903-47-4 | DC Chemicals
Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus.

Product Name: Tizoxanide |Catalog Number:  DC8336 | cas: 173903-47-4 | Other names:  | Chemical name: | Molecule Formula: C10H7N3O4S | MW: 265.3

Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum.Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively),inhibits influenza A replication (EC50s = 0.3-1 μM), and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

For research and scientific purpose only, not for human use.


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