2015年10月25日星期日

Conduritol B Epoxide (CBE) |inhibitor of β-glucosidase|DC Chemicals

Conduritol B Epoxide (CBE) |inhibitor of β-glucosidase|DC Chemicals
Conduritol B Epoxide (CBE) is a specific covalent inhibitor of β-glucosidase which results in the accumulation of glucocerebroside.

Product Name: Conduritol B Epoxide(CBE) |Catalog Number:  DC8340 | cas: 6090-95-5 | Other names: Conduritol C epoxide | Chemical name:D,L-1,2-Anhydro-myo-inositol; 1,2-Anhydro-myo-inositol; Conduritol B-epoxide; Conduritol C epoxide
 | Molecule Formula: C6H10O5 | MW: 162.14

Conduritol B Epoxide (CBE) is a specific covalent inhibitor of β-glucosidase which results in the accumulation of glucocerebroside. Treatment of murine peritoneal macrophages with this inhibitor does not seem to affect lysozyme enzyme release to the medium, cell viability, or levels of intracellular lysosomal enzymes, other than &beta-glucosidase activity. In vitro exposure of cells to CBE has been reported to lead to up-regulation of CD1d (cluster of differentiation 1d) expression by THP-1 cells, which is related to an increase in mRNA expression.

For research and scientific purpose only, not for human use.

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