Naloxone HCl Dihydrate|cas 51481-60-8|DC Chemicals

Naloxone HCl Dihydrate|cas 51481-60-8|DC Chemicals

Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose.

Product Name: Naloxone HCl Dihydrate |Catalog Number:  DC8407 | cas: 51481-60-8 | Other names:  | Chemical name：naloxone hydrochloride dihydrate | Molecule Formula: C19H26ClNO6 | MW: 399.87

The Ki values of (−)-naloxone for the MOR, KOR, and DOR are 0.559 nM, 4.91 nM, and 36.5 nM, respectively. Naloxone HCl Dihydrate binds to the MOR with approximately 9-fold greater affinity relative to the KOR and around 60-fold greater affinity relative to the DOR.[1]The combination of Naloxone HCl Dihydrate (0.5 mg/kg, i.p.) with tramadol (22 mg/kg) decreases the antiallodynic effect of tramadol.

For research and scientific purpose only, not for human use.