MPEP-HCl| mGlu5a receptor inhibitor|DC Chemicals

MPEP-HCl| mGlu5a receptor inhibitor|DC Chemicals
MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM.

Product Name: MPEP hydrochloride |Catalog Number:  DC8339 | cas: 219911-35-0 | Other names:  | Chemical name：2-Methyl-6-(phenylethynyl)pyridine hydrochloride | Molecule Formula: C14H11N.HCl | MW: 229.71

Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.

For research and scientific purpose only, not for human use.