Bromodeoxyuridine (BrdU)|cas 59-14-3|DC Chemicals

Bromodeoxyuridine (BrdU)|cas 59-14-3|DC Chemicals

Bromodeoxyuridine (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA, and used in the detection of proliferating cells.

Product Name: Bromodeoxyuridine (BrdU) |Catalog Number:  DC8386 | cas: 59-14-3 | Other names:  | Chemical name：5-bromo-1-((2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | Molecule Formula: C9H11BrN2O5 | MW: 307.1

In RG2 rat glioma cells, Bromodeoxyuridine induces a progressive, dose-responsive suppression of cancer cell line and cancer stem cell population expansion. In H9 cells and BJ fibroblasts, Bromodeoxyuridine alters the cell cycle profile. [1] BrdU is stably integrated into the DNA, and thus can be used in assessment of cell proliferation and other cell procession. [2]In rat glioma RG2 tumor model, Bromodeoxyuridine (300 mg/kg, i.p. or 0.8 mg/ml, p.o.) significantly slows tumor progression.

For research and scientific purpose only, not for human use.