2015年10月27日星期二

GSK2256098|GSK-2256098|FAK inhibitor

GSK2256098|GSK-2256098|FAK inhibitor|DC Chemicals

GSK2256098 is  small molecule FAK kinase inhibitor.

Product Name: GSK2256098 |Catalog Number:  DC8331 | cas: N/A | Other names: GSK2256098,GSK-2256098,GSK 2256098 | Chemical name: 2-[(5-Chloro-2-{[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino}-4-pyridinyl)amino]-N-(methyloxy)benzamide; 2-[(5-chloro-2-{[3-methyl-1-(propan-2-yl)-1H-pyrazol-5-yl]amino}pyridin-4-yl)amino]-N-methoxybenzamide | Molecule Formula: C20H23ClN6O2 | MW: 414.88

GSK2256098 is  small molecule FAK kinase inhibitor.FAK inhibitor GSK2256098 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thereby inhibiting tumor cell migration, proliferation and survival, and tumor angiogenesis. The tyrosine kinase FAK is normally activated by binding to integrins in the extracellular matrix (ECM) but may be upregulated and constitutively activated in various tumor cell types.

For research and scientific purpose only, not for human use.

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