2015年10月26日星期一

SB-742457(RVT-101)|5-HT6 receptor inhibitor|DC Chemicals

SB-742457(RVT-101)|5-HT6 receptor inhibitor|DC Chemicals

SB-742457, also known as RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.

Product Name: SB-742457(RVT-101) |Catalog Number:  DC8354 | cas: 607742-69-8 | Other names: SB 742457,RVT 101,SB742457,RVT101 | Chemical name:3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline | Molecule Formula: C19H19N3O2S | MW: 353.12

SB-742457, also known as RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.

For research and scientific purpose only, not for human use.

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