BIO-Acetoxime|GSK-3 inhibitor|DC Chemicals

BIO-Acetoxime|GSK-3 inhibitor|DC Chemicals

BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO

Product Name: BIO-Acetoxime |Catalog Number:  DC8368 | cas: 740841-15-0 | Other names: GSK3 Inhibitor X
6-Bromoindirubin-3'-acetoxime | Chemical name：(2'Z,3'E)-6-Bromoindirubin-3'-acetoxime | Molecule Formula: C18H12BrN3O3 | MW: 398.21

BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO.It potently inhibits GSK3α/β (IC50 = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (IC50s = 2.4, 4.3, and 63 µM, respectively).BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway.3 It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells.

For research and scientific purpose only, not for human use.