PRE-084(PRE084)|Sigma-1 inhibitor|DC Chemicals

PRE-084(PRE084)|Sigma-1 inhibitor|DC Chemicals
PRE-084 hydrochloride is a high affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively).

Product Name: PRE-084 hydrochloride |Catalog Number:  DC8347 | cas: 138847-85-5 | Other names: PRE-084,PRE 084,PRE084 | Chemical name：2-(4-Morpholinethyl) 1-phenylcyclohexanecarboxylate hydrochloride | Molecule Formula: C19H27NO3.HCl | MW: 353.89

High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling.

For research and scientific purpose only, not for human use.