LY2119620|cas 886047-22-9|DC Chemicals

LY2119620|cas 886047-22-9|DC Chemicals

LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.

Product Name: LY2119620 |Catalog Number:  DC8435 | cas: 886047-22-9 | Other names: LY2119620,LY-2119620,LY 2119620 | Chemical name：3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide | Molecule Formula: C19H24ClN5O3S | MW: 437.94

LY2119620 displays modest allosteric agonism and positively modulates the functional G protein–signaling ability of an agonist at the M2/M4 receptor subtypes by placing the M2 and M4 receptors into an active G protein–bound state. LY2119620 enhances the potency of three muscarinic acetylcholine receptor agonists, ACh, Oxo-M and iperoxo. [1] [3H]LY2119620 can be used as a probe for the human M(2) and M(4) muscarinic receptor allosteric binding sites.

For research and scientific purpose only, not for human use.