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Product name: OSI-906, Synonym: OSI 906,OSI906, Cat No. DC4105, Cas: 867160-71-2, Chemical Name:(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol, Molecular Formula: C26H23N5O, MW: 421.49
OSI-906 Cas#867160-71-2.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! OSI-906 (Linsitinib) is a selective inhibitor of IGF-1R and IR with IC50 of 35 nM and 75 nM, respectively.
Description of Linsitinib (OSI-906): Linsitinib (OSI-906) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). OSI-906 is currently developed by OSI Pharmaceuticals, Inc. see http://www.osip.com.
For the detailed information about the solubility of OSI-906 in water, the solubility of OSI-906 in DMSO, the solubility of OSI-906 in PBS buffer, the animal experiment of OSI-906,the in vivo and in vitro test of OSI-906,the cell experiment of OSI-906,the IC50 and EC50 of OSI-906please contact DC Chemicals.
For the detailed information about the solubility of OSI-906 in water, the solubility of OSI-906 in DMSO, the solubility of OSI-906 in PBS buffer, the animal experiment of OSI-906,the in vivo and in vitro test of OSI-906,the cell experiment of OSI-906,the IC50 and EC50 of OSI-906please contact DC Chemicals.
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