NVP-HSP990 (HSP990) |cas 934343-74-5 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: NVP-HSP990 (HSP990)  ,cas 934343-74-5, Cat No. DC4178, In stock

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Product name: NVP-HSP990 (HSP990), Synonym:　N/A, Cat No. DC4178, Cas: 934343-74-5, Chemical Name:N/A, Molecular Formula: C20H18FN5O2, MW: 379.38762

NVP-HSP990 (HSP990) Cas#934343-74-5.Purity:99%.Best Price and Quality in the Market!Supplied by DC Chemicals! HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

Description of HSP-990: HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp990 binds to and inhibits the activity of Hsp90, which may result in the proteasomal degradation of oncogenic client proteins, including HER2/ERBB2, and the inhibition of tumor cell proliferation. Hsp90, upregulated in a variety of tumor cells, is a molecular chaperone that plays a key role in the conformational maturation, stability and function of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation and/or immune responses. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
For the detailed information about the solubility of NVP-HSP990 (HSP990)  in water, the solubility of NVP-HSP990 (HSP990)  in DMSO, the solubility of NVP-HSP990 (HSP990)  in PBS buffer, the animal experiment of NVP-HSP990 (HSP990) ,the in vivo and in vitro test of NVP-HSP990 (HSP990) ,the cell experiment of NVP-HSP990 (HSP990) ,the IC50 and EC50 of NVP-HSP990 (HSP990) please contact DC Chemicals.