Oprozomib (ONX-0912) |cas 935888-69-0 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: Oprozomib (ONX-0912) ,cas 935888-69-0, Cat No. DC2010, In stock

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Product name: Oprozomib (ONX-0912), Synonym:　Oprozomib, ONX0912, Cat No. DC2010, Cas: 935888-69-0, Chemical Name:L-Serinamide, O-methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-, Molecular Formula: C25H32N4O7S, MW: 532.61

Oprozomib (ONX-0912) Cas#935888-69-0.Purity:>98%.Best Price and Quality in the Market!Supplied by DC Chemicals! Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.

Description of Oprozomib (ONX 0912): ONX 0912 is an orally bioavailable proteasome inhibitor with potential antineoplastic activity. ONX 0912 inhibits the activity of the proteasome, thereby blocking the targeted proteolysis normally performed by the proteasome; this may result in an accumulation of unwanted or misfolded proteins. Disruption of various cell signaling pathways may follow, eventually leading to the induction of apoptosis and inhibition of tumor growth. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquitinated. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
For the detailed information about the solubility of Oprozomib (ONX-0912) in water, the solubility of Oprozomib (ONX-0912) in DMSO, the solubility of Oprozomib (ONX-0912) in PBS buffer, the animal experiment of Oprozomib (ONX-0912),the in vivo and in vitro test of Oprozomib (ONX-0912),the cell experiment of Oprozomib (ONX-0912),the IC50 and EC50 of Oprozomib (ONX-0912)please contact DC Chemicals.