(+)-JQ1 supplier|cas 1268524-70-4 |DC Chemicals|Supplier|Price|Buy

DC Chemicals Supply: (+)-JQ1 supplier,cas 1268524-70-4, Cat No. DC5019, In stock

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Product name: (+)-JQ1, Synonym:　JQ-1, Cat No. DC5019, Cas: 1268524-70-4, Chemical Name:N/A, Molecular Formula: C23H25ClN4O2S, MW: 456.99

(+)-JQ1,cas 1268524-70-4, Purity: >98%. Best Price and quality in the market,DC Chemicals,Primary Manufacturer, confirmed by HNMR and HPLC. (+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.

(+)-JQ-1 is a potent, high affinity, selective BET bromodomain inhibitor (IC50 values are 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP respectively; Kd values are 49, 59.5, 82, 90.1, 128 and 190 nM for BRD4 (N), BRD3 (N), BRD3 (C), BRD4 (C), BRD2 (N) and BRDT (N) respectively). Induces squamous differentiation in NUT midline carcinoma (NMC) cell lines; inhibits tumor growth in NMC xenograft models in vivo. Exhibits reversible contraceptive effects in germ cells from male mice.