2015年6月23日星期二

PF3845yne(PF 3845yne)|analogues of PF3845|DC Chemicals

PF3845yne(PF 3845yne)|analogues of PF3845|DC Chemicals
PF3845yne is a Alkyne analogues of PF3845.

Product name: PF3845yne |Cat No. DC8152|Other names: PF3845yne,PF3845 yne,PF3845-yne,PF 3845 yne|Cas: 1196109-53-1|Molecule Weight: 412.48366|Molecule Formular: C25H24N4O2| Purity: >98%

Both PF3845yne and JP104 selectively reacted with a single brain protein, which was confirmed to be FAAH based on its absent from FAAH(−/−) mice. In liver, however, PF3845yne and JP104 showed strikingly different profiles, with the former agent once again showing selective reactivity with FAAH and the latter inhibitor labeling a number of proteins. These data indicate that PF-3845 inhibits FAAH in vivo with exceptional efficacy and selectivity.

For research and scientific purpose only, not for human use.

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