TCS 5861528|TRPA1 channel blocker|DC Chemials

TCS 5861528|TRPA1 channel blocker|DC Chemials

TCS 5861528 is a TRPA1 channel blocker and an antagonizer of AITC- and 4-HNE-evoked calcium influx.

Product name: TCS 5861528 |Cat No. DC8262|Other names: TCS 5861528  ,TCS 5861528,TCS 5861528 |Cas: 332117-28-9|Molecule Weight: 369.42|Molecule Formular: C19H23N5O3| Purity: >98%

Selective TRPA1 channel blocker (IC50 values are 14.3 and 18.7 µM for AITC- and 4-HNE- evoked Ca2+ influx respectively). Exhibits little of no activity at TRPV1 channels. Reduces mechanical hypersensitivity, attenuates diabetes mellitus hypersensitivity and displays antinociceptive properties.

For research and scientific purpose only, not for human use.